上海信帆生物供应：膀胱肿瘤抗原

中文名称

膀胱肿瘤抗原

别名

补体因子H（Complement Factor H）是膀胱肿瘤抗原（Bladder Tumor Antigen, BTA）的具体成分，是由尿路上皮肿瘤细胞和巨噬细胞产生的，不是正常表皮细胞产生的

英文别名

BTA; complement factor H; complement factor H, isoform b; Factor H; factor H like 1; FH; FHL 1; FHL1; H factor 1 (complement); H factor 1; H factor 2 (complement); HF 1; HF 2; HF; HF1; HF2; HUS; MGC88246.  

性    状

Lyophilized powder

多肽活性

多肽

产品来源

合成

纯化方法

HPLC

产品应用

Blocking Peptide of The Antibody

保存条件

Store at -20 °C for one year.

产品介绍

This is one synthetic peptide derived from human Factor H.
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Oct 2011] Function : Factor H functions as a cofactor in the inactivation of C3b by factor I and also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway.